Publications and Impact factor

Over the years the scientific production of IOV researchers has grown considerably, placing the Institute at the top of the national level. After the great leap (+ 22.5%) between 2016 and 2015, in 2017 the number of publications communicated to the Ministry of Health increased from 234 to 237 and, in 2018, to 256. A large part of them has found a place in the top ten most prestigious journals worldwide.

Publications and Impact factor
Year
N ° publications
normalized IF
IF/researcher
IF /researcher with publications
2018
256
1.219,14
7,85
8,58
2017
237
1.275,7
10,22
13,06
2016
234
1.235,8
8,18
10,31
Top 15 pubblicazioni 2018
TitoloAutoriRivistaIF grezzo
Cabozantinib in patients with advanced and progressing hepatocellular carcinomaAbou-Alfa Ghassan K., Meyer Tim, Cheng Ann Lii, El-Khoueiry Anthony B., Rimassa Lorenza, Ryoo Baek Yeol, Cicin Irfan, Merle Philippe, Chen Yen Hsun, Park Joong Won, Blanc Jean Frederic, Bolondi Luigi, Kl¿¿mpen Heinz Josef, Chan Stephen L., zagonel vittorina, Pressiani Tiziana, Ryu Min Hee, Venook Alan P., Hessel Colin, Borgman-Hagey Anne E., Schwab Gisela, Kelley Robin K.NEW ENGLAND JOURNAL OF MEDICINE79.26
Addition of dose-intensified doxorubicin to standard chemotherapy for rhabdomyosarcoma (EpSSG RMS 2005): a multicentre, open-label, randomised controlled, phase 3 trialGroup European paediatric Soft tissue sarcoma Study, Bisogno Gianni, Jenney Meriel, Bergeron Christophe, Gallego Melc¿¿n Soledad, Ferrari Andrea, Oberlin Odile, Carli Modesto, Stevens Michael, Kelsey Anna, De Paoli Angela, Gaze Mark N, Martelli Helene, Devalck Christine, Merks Johannes H, Ben-Arush Myriam, Glosli Heidi, Chisholm Julia, Orbach Daniel, Minard-Colin Veronique, De Salvo Gian LucaLANCET ONCOLOGY36.421
Encorafenib plus binimetinib versus vemurafenib or encorafenib in patients with BRAF-mutant melanoma (COLUMBUS) a multicentre, open-label, randomised phase 3 trialDummer Reinhard, Ascierto Paolo A, Gogas Helen J, Arance Ana, Mandala Mario, Liszkay Gabriella, Garbe Claus, Schadendorf Dirk, Krajsova Ivana, Gutzmer Ralf, chiarion sileni vanna, Dutriaux Caroline, de Groot Jan Willem B, Yamazaki Naoya, Loquai Carmen, Moutouh-de Parseval Laure A, Pickard Michael D, Sandor Victor, Robert Caroline, Flaherty Keith TLANCET ONCOLOGY36.421
Health-related quality of life and patient-centred outcomes with olaparib maintenance after chemotherapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT Ov-21) a placebo-controlled, phase 3 randomised trialFriedlander Michael, Gebski Val, Gibbs Emma, Davies Lucy, Bloomfield Ralph, Hilpert Felix, Wenzel Lari B., Eek Daniel, Rodrigues Manuel, Clamp Andrew, Penson Richard T., Provencher Diane, Korach Jacob, Huzarski Tomasz, Vidal Laura, Salutari Vanda, Scott Clare, NICOLETTO MARIA ORNELLA, Tamura Kenji, Espinoza David, Joly Florence, Pujade-Lauraine EricLANCET ONCOLOGY36.421
Nivolumab plus ipilimumab or nivolumab alone versus ipilimumab alone in advanced melanoma (CheckMate 067) 4-year outcomes of a multicentre, randomised, phase 3 trialHodi Frank Stephen, chiarion sileni vanna, Gonzalez Rene, Grob Jean-Jacques, Rutkowski Piotr, Cowey Charles Lance, Lao Christopher D, Schadendorf Dirk, Wagstaff John, Dummer Reinhard, Ferrucci Pier Francesco, Smylie Michael, Hill Andrew, Hogg David, Marquez-Rodas Ivan, Jiang Joel, Rizzo Jasmine, Larkin James, Wolchok Jedd DLANCET ONCOLOGY36.421
Overall survival in patients with BRAF-mutant melanoma receiving encorafenib plus binimetinib versus vemurafenib or encorafenib (COLUMBUS): a multicentre, open-label, randomised, phase 3 trialDummer R., Ascierto P.A., Gogas H.J., Arance A., Mandala M., Liszkay G., Garbe C., Schadendorf D., Krajsova I., Gutzmer R., chiarion sileni vanna, Dutriaux C., de Groot J.W.B., Yamazaki N., Loquai C., Moutouh-de Parseval L.A., Pickard M.D., Sandor V., Robert C., Flaherty K.T.LANCET ONCOLOGY36.421
Pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib (KEYNOTE-224) a non-randomised, open-label phase 2 trialKEYNOTE-224 investigators Gruppo, Zhu Andrew X, Finn Richard S, Edeline Julien, Cattan Stephane, Ogasawara Sadahisa, Palmer Daniel, Verslype Chris, zagonel vittorina, Fartoux Laetitia, Vogel Arndt, Sarker Debashis, Verset Gontran, Chan Stephen L, Knox Jennifer, Daniele Bruno, Webber Andrea L, Ebbinghaus Scot W, Ma Junshui, Siegel Abby B, Cheng Ann-Lii, Kudo MasatoshiLANCET ONCOLOGY36.421
Regorafenib compared with lomustine in patients with relapsed glioblastoma (REGOMA) a multicentre, open-label, randomised, controlled, phase 2 trialLOMBARDI GIUSEPPE, De Salvo Gian Luca, Brandes Alba Ariela, Eoli Marica, Rud¿¿ Roberta, Faedi Marina, Lolli Ivan, Pace Andrea, Daniele Bruno, Pasqualetti Francesco, Rizzato Simona, Bellu Luisa, Pambuku Ardi, Farina Miriam, Magni Giovanna, Indraccolo Stefano, Gardiman Marina Paola, Soffietti Riccardo, zagonel vittorinaLANCET ONCOLOGY36.421
Tivantinib for second-line treatment of MET-high, advanced hepatocellular carcinoma (METIV-HCC) a final analysis of a phase 3, randomised, placebo-controlled studyRimassa Lorenza, Assenat Eric, Peck-Radosavljevic Markus, Pracht Marc, zagonel vittorina, Mathurin Philippe, Rota Caremoli Elena, Porta Camillo, Daniele Bruno, Bolondi Luigi, Mazzaferro Vincenzo, Harris William, Damjanov Nevena, Pastorelli Davide, Reig Mar¿¿a, Knox Jennifer, Negri Francesca, Trojan J¿¿rg, L¿¿pez L¿¿pez Carlos, Personeni Nicola, Decaens Thomas, Dupuy Marie, Sieghart Wolfgang, Abbadessa Giovanni, Schwartz Brian, Lamar Maria, Goldberg Terri, Shuster Dale, Santoro Armando, Bruix JordiLANCET ONCOLOGY36.421
Cisplatin-based first-line treatment of elderly patients with advanced non-small-cell lung cancer: Joint analysis of MILES-3 and MILES-4 phase III trialsGridelli C., Morabito A., Cavanna L., Luciani A., Maione P., Bonanno Laura, Filipazzi V., Leo S., Cinieri S., Ciardiello F., Burgio M.A., Bilancia D., Cortinovis D., Rosetti F., Bianco R., Gebbia V., Artioli F., Bordonaro R., Fregoni V., Mencoboni M., Nelli F., Riccardi F., Di Isernia G., Costanzo R., Rocco G., Daniele G., Signoriello S., Piccirillo M.C., Gallo C., Perrone F.JOURNAL OF CLINICAL ONCOLOGY26.36
BRAF V600E Confers Male Sex Disease-Specific Mortality Risk in Patients With Papillary Thyroid CancerWang Fei, Zhao Shihua, Shen Xiaopei, Zhu Guangwu, Liu Rengyun, Viola David, Elisei Rossella, Puxeddu Efisio, Fugazzola Laura, Colombo Carla, Jarzab Barbara, Czarniecka Agnieszka, Lam Alfred K, Mian Caterina, Vianello Federica, Yip Linwah, Riesco-Eizaguirre Garcilaso, Santisteban Pilar, O'Neill Christine J, Sywak Mark S, Clifton-Bligh Roderick, Bendlova Bela, S¿¿korov¿¿ Vlasta, Wang Yangang, Xing MingzhaoJOURNAL OF CLINICAL ONCOLOGY26.36
Demographic and Treatment Variables Influencing Outcome for Localized Paratesticular Rhabdomyosarcoma: Results From a Pooled Analysis of North American and European Cooperative GroupsWalterhouse David O, Barkauskas Donald A, Hall David, Ferrari Andrea, De Salvo Gian Luca, Koscielniak Ewa, Stevens Michael C G, Martelli H¿¿l¿¿ne, Seitz Guido, Rodeberg David A, Shnorhavorian Margarett, Dasgupta Roshni, Breneman John C, Anderson James R, Bergeron Christophe, Bisogno Gianni, Meyer William H, Hawkins Douglas S, Minard-Colin VeroniqueJOURNAL OF CLINICAL ONCOLOGY26.36
Durable Clinical Benefit With Nivolumab Plus Ipilimumab in DNA Mismatch Repair-Deficient/Microsatellite Instability-High Metastatic Colorectal CancerOverman Michael J, Lonardi Sara, Wong Ka Yeung Mark, Lenz Heinz-Josef, Gelsomino Fabio, Aglietta Massimo, Morse Michael A, Van Cutsem Eric, McDermott Ray, Hill Andrew, Sawyer Michael B, Hendlisz Alain, Neyns Bart, Svrcek Magali, Moss Rebecca A, Ledeine Jean-Marie, Cao Z Alexander, Kamble Shital, Kopetz Scott, Andr¿¿ ThierryJOURNAL OF CLINICAL ONCOLOGY26.36
FOLFOX or CAPOX in Stage II to III Colon Cancer: Efficacy Results of the Italian Three or Six Colon Adjuvant TrialInvestigators TOSCA, Sobrero Alberto, Lonardi Sara, Rosati Gerardo, Di Bartolomeo Maria, Ronzoni Monica, Pella Nicoletta, Scartozzi Mario, Banzi Maria, Zampino Maria Giulia, Pasini Felice, Marchetti Paolo, Cantore Maurizio, Zaniboni Alberto, Rimassa Lorenza, Ciuffreda Libero, Ferrari Daris, zagonel vittorina, Maiello Evaristo, Barni Sandro, Rulli Eliana, Labianca RobertoJOURNAL OF CLINICAL ONCOLOGY26.36
Longer Follow-Up Confirms Relapse-Free Survival Benefit With Adjuvant Dabrafenib Plus Trametinib in Patients With Resected BRAF V600-Mutant Stage III MelanomaHauschild Axel, Dummer Reinhard, Schadendorf Dirk, Santinami Mario, Atkinson Victoria, Mandal¿¿ Mario, chiarion sileni vanna, Larkin James, Nyakas Marta, Dutriaux Caroline, Haydon Andrew, Robert Caroline, Mortier Laurent, Schachter Jacob, Lesimple Thierry, Plummer Ruth, Dasgupta Kohinoor, Haas Tomas, Shilkrut Mark, Gasal Eduard, Kefford Richard, Kirkwood John M, Long Georgina VJOURNAL OF CLINICAL ONCOLOGY26.36
Top 15 pubblicazioni 2017
TitoloAutoriRivistaIF grezzo
Melanoma staging: Evidence-based changes in the American Joint Committee on Cancer eighth edition cancer staging manualGershenwald,J. E., Scolyer,R. A., Hess,K. R., Sondak,V. K., Long,G. V., Ross,M. I., Lazar,A. J., Faries,M. B., Kirkwood,J. M., McArthur,G. A., Haydu,L. E., Eggermont,A. M. M., Flaherty,K. T., Balch,C. M., Thompson,J. F., for members of the American Joint Committee on Can, Rossi Carlo Riccardo, Sommariva Antonio, Del Fiore Santo PaoloCA-A Cancer Journal for Clinicians187,04
Completion Dissection or Observation for Sentinel-Node Metastasis in MelanomaFaries,M. B., Thompson,J. F., Cochran,A. J., Andtbacka,R. H., Mozzillo,N., Zager,J. S., Jahkola,T., Bowles,T. L., Testori,A., Beitsch,P. D., Hoekstra,H. J., Moncrieff,M., Ingvar,C., Wouters,M. W. J. M., Sabel,M. S., Levine,E. A., Agnese,D., Henderson,M., Dummer,R., Rossi Carlo Riccardo (...)The New England Journal of Medicine72,406
Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA MutationRobson,M., Im,S. A., Senkus,E., Xu,B., Domchek,S. M., Masuda,N., Delaloge,S., Li,W., Tung,N., Armstrong,A., Wu,W., Goessl,C., Runswick,S., Conte PierFrancoThe New England Journal of Medicine72,406
Abiraterone plus Prednisone in Metastatic, Castration-Sensitive Prostate CancerFizazi,K., Tran,N., Fein,L., Matsubara,N., Rodriguez-Antolin,A., Alekseev,B. Y., Ozguroglu,M., Ye,D., Feyerabend,S., Protheroe,A., De Porre,P., Kheoh,T., Park,Y. C., Todd,M. B., Chi,K. N., LATITUDE Investigators, Basso UmbertoThe New England Journal of Medicine72,406
Overall Survival with Combined Nivolumab and Ipilimumab in Advanced MelanomaWolchok,J. D., Chiarion-Sileni Vanna, Gonzalez,R., Rutkowski,P., Grob,J. J., Cowey,C. L., Lao,C. D., Wagstaff,J., Schadendorf,D., Ferrucci,P. F., Smylie,M., Dummer,R., Hill,A., Hogg,D., Haanen,J., Carlino,M. S., Bechter,O., Maio,M., Marquez-Rodas,I., Guidoboni,M. (...)The New England Journal of Medicine72,406
Adjuvant Dabrafenib plus Trametinib in Stage III BRAF-Mutated MelanomaLong,G. V., Hauschild,A., Santinami,M., Atkinson,V., Mandala,M., Chiarion-Sileni Vanna, Larkin,J., Nyakas,M., Dutriaux,C., Haydon,A., Robert,C., Mortier,L., Schachter,J., Schadendorf,D., Lesimple,T., Plummer,R., Ji,R., Zhang,P., Mookerjee,B., Legos,J. (...)The New England Journal of Medicine72,406
Adjuvant Nivolumab versus Ipilimumab in Resected Stage III or IV MelanomaWeber,J., Mandala,M., Del Vecchio,M., Gogas,H. J., Arance,A. M., Cowey,C. L., Dalle,S., Schenker,M., Chiarion-Sileni Vanna, Marquez-Rodas,I., Grob,J. J., Butler,M. O., Middleton,M. R., Maio,M., Atkinson,V., Queirolo,P., Gonzalez,R., Kudchadkar,R. R., Smylie,M., Meyer,N. (...)The New England Journal of Medicine72,406
Ipilimumab 10 mg/kg versus ipilimumab 3 mg/kg in patients with unresectable or metastatic melanoma: a randomised, double-blind, multicentre, phase 3 trialAscierto,P. A., Del Vecchio,M., Robert,C., Mackiewicz,A., Chiarion-Sileni Vanna, Arance,A., Lebbé,C., Bastholt,L., Hamid,O., Rutkowski,P., McNeil,C., Garbe,C., Loquai,C., Dreno,B., Thomas,L., Grob,J. -J, Liszkay,G., Nyakas,M., Gutzmer,R., Pikiel,J. (...)Lancet Oncology33,9
Histotype-tailored neoadjuvant chemotherapy versus standard chemotherapy in patients with high-risk soft-tissue sarcomas (ISG-STS 1001): an international, open-label, randomised, controlled, phase 3, multicentre trialGronchi,A., Ferrari,S., Quagliuolo,V., Broto,J. M., Pousa,A. L., Grignani,G., Basso Umberto, Blay,J. Y., Tendero,O., Beveridge,R. D., Ferraresi,V., Lugowska,I., Merlo,D. F., Fontana,V., Marchesi,E., Donati,D. M., Palassini,E., Palmerini,E., De Sanctis,R., Morosi,C. (...)Lancet Oncology33,9
Dabrafenib plus trametinib in patients with BRAFV600-mutant melanoma brain metastases (COMBI-MB): a multicentre, multicohort, open-label, phase 2 trialDavies,M. A., Saiag,P., Robert,C., Grob,J. J., Flaherty,K. T., Arance,A., Chiarion-Sileni Vanna, Thomas,L., Lesimple,T., Mortier,L., Moschos,S. J., Hogg,D., Marquez-Rodas,I., Del Vecchio,M., Lebbe,C., Meyer,N., Zhang,Y., Huang,Y., Mookerjee,B., Long,G. V. (...)Lancet Oncology33,9
Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 studyOverman,M. J., McDermott,R., Leach,J. L., Lonardi Sara, Lenz,H. J., Morse,M. A., Desai,J., Hill,A., Axelson,M., Moss,R. A., Goldberg,M. V., Cao,Z. A., Ledeine,J. M., Maglinte,G. A., Kopetz,S., Andre,T.Lancet Oncology33,9
New perspectives for TAS-102: TASK successful?Loupakis Fotios, Lonardi SaraLancet Oncology33,9
Ipatasertib plus paclitaxel versus placebo plus paclitaxel as first-line therapy for metastatic triple-negative breast cancer (LOTUS): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trialKim,S. B., Dent,R., Im,S. A., Espie,M., Blau,S., Tan,A. R., Isakoff,S. J., Oliveira,M., Saura,C., Wongchenko,M. J., Kapp,A. V., Chan,W. Y., Singel,S. M., Maslyar,D. J., Baselga,J., LOTUS investigators, Conte PierFrancoLancet Oncology33,9
Health-related quality of life with adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): Secondary outcomes of a multinational, randomised, double-blind, phase 3 trialCoens,C., Suciu,S., Chiarion-Sileni Vanna, Grob,J. -J, Dummer,R., Wolchok,J. D., Schmidt,H., Hamid,O., Robert,C., Ascierto,P. A., Richards,J. M., Lebbé,C., Ferraresi,V., Smylie,M., Weber,J. S., Maio,M., Bottomley,A., Kotapati,S., de Pril,V., Testori,A. (...)Lancet Oncology33,9
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancerPhelan,C. M., Kuchenbaecker,K. B., Tyrer,J. P., Kar,S. P., Lawrenson,K., Winham,S. J., Dennis,J., Pirie,A., Riggan,M. J., Chornokur,G., Earp,M. A., Lyra,P. C.,Jr, Lee,J. M., Coetzee,S., Beesley,J., McGuffog,L., Soucy,P., Dicks,E., Lee,A., Barrowdale,D. (...)
Nature Genetics
27,959
Top 10 pubblicazioni 2016
TitoloAutoriRivistaIF grezzo
CDX2 as a Prognostic Biomarker in Colon CancerSchirripa,M., Loupakis Fotios, Lenz,H. -JThe New England Journal of Medicine59,558
Prolonged Survival in Stage III Melanoma with Ipilimumab Adjuvant TherapyEggermont,A. M., Chiarion-Sileni Vanna, Grob,J. J., Dummer,R., Wolchok,J. D., Schmidt,H., Hamid,O., Robert,C., Ascierto,P. A., Richards,J. M., Lebbe,C., Ferraresi,V., Smylie,M., Weber,J. S., Maio,M., Bastholt,L., Mortier,L., Thomas,L., Tahir,S., Hauschild,A. (...)The New England Journal of Medicine59,558
Ribociclib as First-Line Therapy for HR-Positive, Advanced Breast CancerHortobagyi,G. N., Stemmer,S. M., Burris,H. A., Yap,Y. S., Sonke,G. S., Paluch-Shimon,S., Campone,M., Blackwell,K. L., Andre,F., Winer,E. P., Janni,W., Verma,S., Conte PierFranco, Arteaga,C. L., Cameron,D. A., Petrakova,K., Hart,L. L., Villanueva,C., Chan,A., Jakobsen,E. (...)The New England Journal of Medicine59,558
Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170Dunning,A. M., Michailidou,K., Kuchenbaecker,K. B., Thompson,D., French,J. D., Beesley,J., Healey,C. S., Kar,S., Pooley,K. A., Lopez-Knowles,E., Dicks,E., Barrowdale,D., Sinnott-Armstrong,N. A., Sallari,R. C., Hillman,K. M., Kaufmann,S., Sivakumaran,H., Moradi Marjaneh,M., Lee,J. S., Hills,M. (...)Nature genetics31,616
Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trialSartore-Bianchi,A., Trusolino,L., Martino,C., Bencardino,K., Lonardi Sara, Bergamo Francesca, Zagonel Vittorina, Leone,F., Depetris,I., Martinelli,E., Troiani,T., Ciardiello,F., Racca,P., Bertotti,A., Siravegna,G., Torri,V., Amatu,A., Ghezzi,S., Marrapese,G., Palmeri,L. (...)Lancet Oncology26,509
Toxicity and quality of life after adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): an open-label, multicentre, randomised, phase 3 trialde Boer,S. M., Powell,M. E., Mileshkin,L., Katsaros,D., Bessette,P., Haie-Meder,C., Ottevanger,P. B., Ledermann,J. A., Khaw,P., Colombo,A., Fyles,A., Baron,M. H., Kitchener,H. C., Nijman,H. W., Kruitwagen,R. F., Nout,R. A., Verhoeven-Adema,K. W., Smit,V. T., Putter,H., Creutzberg,C. L. (...)Lancet Oncology26,509
T Cell Cancer Therapy Requires CD40-CD40L Activation of Tumor Necrosis Factor and Inducible Nitric-Oxide-Synthase-Producing Dendritic CellsMarigo Ilaria , Zilio,S., Desantis Giacomo, Mlecnik,B., Agnellini,A. H., Ugel,S., Sasso,M. S., Qualls,J. E., Kratochvill,F., Zanovello Paola, Molon Barbara, Ries,C. H., Runza,V., Hoves,S., Bilocq,A. M., Bindea,G., Mazza,E. M., Bicciato,S., Galon,J., Murray,P. J. (...)Cancer Cell23,214
Induction of Expandable Tissue-Specific Stem/Progenitor Cells through Transient Expression of YAP/TAZPanciera,T., Azzolin,L., Fujimura,A., Di Biagio,D., Frasson,C., Bresolin,S., Soligo,S., Basso,G., Bicciato,S., Rosato Antonio, Cordenonsi,M., Piccolo,S.Cell Stem Cell22,387
Reliable Detection of Mismatch Repair Deficiency in Colorectal Cancers Using Mutational Load in Next-Generation Sequencing PanelsStadler,Z. K., Battaglin Francesca, Middha,S., Hechtman,J. F., Tran,C., Cercek,A., Yaeger,R., Segal,N. H., Varghese,A. M., Reidy-Lagunes,D. L., Kemeny,N. E., Salo-Mullen,E. E., Ashraf,A., Weiser,M. R., Garcia-Aguilar,J., Robson,M. E., Offit,K., Arcila,M. E., Berger,M. F., Shia,J. (...)Journal of Clinical Oncology20,982
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancerWalerych,D., Lisek,K., Sommaggio,R., Piazza,S., Ciani,Y., Dalla,E., Rajkowska,K., Gaweda-Walerych,K., Ingallina,E., Tonelli,C., Morelli,M. J., Amato,A., Eterno,V., Zambelli,A., Rosato Antonio, Amati,B., Wisniewski,J. R., Del Sal,G.Nature cell biology18,699

The top IOV publications 2016-2018 published in the most prestigious journals worldwide

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